Mensagem em tempo de design is not a sibling in the same constraintlayout
Na seguinte linha: app:layout_constraintBottom_toTopOf="@+id/item_pacote_imagem" -->aqui Pelo que vi a referência em camadas diferentes deu pau... Segue arquivo completo
<?xml version="1.0" encoding="utf-8"?>
<android.support.constraint.ConstraintLayout xmlns:android="http://schemas.android.com/apk/res/android"
android:layout_width="match_parent"
android:layout_height="match_parent"
xmlns:app="http://schemas.android.com/apk/res-auto"
xmlns:tools="http://schemas.android.com/tools">
<android.support.v7.widget.CardView
android:id="@+id/item_pacote_cardview"
android:layout_width="0dp"
android:layout_height="wrap_content"
android:layout_margin="8dp"
app:cardCornerRadius="10dp"
app:layout_constraintBottom_toTopOf="@+id/item_pacote_imagem" <b>-->aqui </b>
app:layout_constraintEnd_toEndOf="parent"
app:layout_constraintStart_toStartOf="parent"
app:layout_constraintTop_toTopOf="parent">
<android.support.constraint.ConstraintLayout
android:layout_width="match_parent"
android:layout_height="match_parent">
<ImageView
android:id="@+id/item_pacote_imagem"
android:layout_width="0dp"
android:layout_height="100dp"
android:scaleType="centerCrop"
app:layout_constraintEnd_toEndOf="parent"
app:layout_constraintStart_toStartOf="parent"
app:layout_constraintTop_toTopOf="parent"
tools:src="@sample/pacote.json/pacotes/imagem" />
<TextView
android:id="@+id/item_pacote_local"
android:layout_width="wrap_content"
android:layout_height="wrap_content"
android:layout_margin="8dp"
android:background="@android:drawable/screen_background_dark_transparent"
android:padding="8dp"
android:textColor="@android:color/white"
android:textSize="14sp"
android:textStyle="bold"
app:layout_constraintBottom_toBottomOf="@id/item_pacote_imagem"
app:layout_constraintEnd_toEndOf="@id/item_pacote_imagem"
app:layout_constraintHorizontal_bias="0.0"
app:layout_constraintStart_toStartOf="@+id/item_pacote_imagem"
app:layout_constraintTop_toTopOf="@id/item_pacote_imagem"
app:layout_constraintVertical_bias="1.0"
tools:text="@sample/pacote.json/pacotes/local" />
<View
android:id="@+id/item_pacote_divisor"
android:layout_width="0dp"
android:layout_height="3dp"
android:background="@android:color/holo_orange_dark"
app:layout_constraintEnd_toEndOf="parent"
app:layout_constraintStart_toStartOf="parent"
app:layout_constraintTop_toBottomOf="@id/item_pacote_imagem" />
<TextView
android:id="@+id/item_pacote_dias"
android:layout_width="wrap_content"
android:layout_height="wrap_content"
android:layout_margin="8dp"
android:textSize="16sp"
android:textStyle="bold"
app:layout_constraintEnd_toEndOf="parent"
app:layout_constraintHorizontal_bias="0.0"
app:layout_constraintStart_toStartOf="parent"
app:layout_constraintTop_toBottomOf="@id/item_pacote_divisor"
tools:text="@sample/pacote.json/pacotes/dias" />
<TextView
android:id="@+id/item_pacote_preco"
android:layout_width="wrap_content"
android:layout_height="wrap_content"
android:textColor="@android:color/holo_green_dark"
android:textSize="20sp"
app:layout_constraintStart_toStartOf="@id/item_pacote_dias"
app:layout_constraintTop_toBottomOf="@id/item_pacote_dias"
tools:text="@sample/pacote.json/pacotes/preco" />
</android.support.constraint.ConstraintLayout>
</android.support.v7.widget.CardView>
</android.support.constraint.ConstraintLayout>